Clinical Indications
CryoDose TA temporarily controls pain associated with injections, starting IVs, venipuncture, minor surgical procedures, and more. CryoDose TA is FDA-cleared for use on intact mucous membranes including the oral cavity, lips, and nasal passages.
Indications for Use
Do More with CryoDose TA
CryoDose TA is intended for topical application to the skin, intact mucous membranes (oral cavity, nasal passageways, and lips), and minor open wounds. You can safely use this topical anesthetic spray for pain management for the following possible uses and more.
Injections
- IV Starts
- Joint Injections
- PRP Injections
- Vaccinations
- Cosmetic Procedures – Fillers, BOTOX®, Pre-lidocaine Injections
- Venipuncture
Minor surgical
procedures
- I&D of Abscess, Paronychia, Bursa
- Lancing Boils
- Suturing, Stapling
- Removal of Staples, Sutures, Pins, and Other Hardware
- Wound Debridement
- Foreign Body Removal (e.g., Splinter)
Temporary relief of minor sports injuries
- Sprains
- Bruising
- Cuts and Abrasions
How to Use
CryoDose TA
About Ethyl Chloride
- Many hazardous chemicals are present in healthcare settings, which may pose an exposure risk for healthcare workers.
- Ethyl Chloride is a known liver and kidney toxin and is categorized by the ACGIH as A3, confirmed animal carcinogen.
- Ethyl Chloride is a general anesthetic and comes with inhalation precautions.
- Because Ethyl Chloride is slightly absorbed, it is cleared for use on intact skin only.
- Ethyl Chloride is one of the last remaining glass items in a healthcare setting.
Healthcare professionals are at increased risk for chemical and pharmaceutical exposure. The National Institute for Occupational Safety and Health (NIOSH) found mounting evidence that healthcare professionals are being widely exposed to both hazardous drugs and chemical hazards in the workplace.*
*National Institute for Occupational Safety and Health (2009). State of the Sector. Healthcare and Social Assistance. Learn More
Risks of
Ethyl Chloride
Ethyl Chloride by many measures is dangerous to humans through inhalation and skin absorption. The known dangers to humans from Ethyl Chloride use are as follows:
CryoDose TA is:
About CryoDose TA
- Over 10,000 healthcare facilities have converted to CryoDose TA topical anesthetic spray as it is non-toxic, non-flammable, HAZMAT-free and, because it 100% evaporates, is cleared for more uses including minor open wounds and intact mucous membranes.
- More indications over Ethyl Chloride: because it 100% evaporates, it can be used on open wounds, such as for removing hardware (pins, sutures, etc.).
- Equal cooling and anesthetic effect: studies have concluded that Ethyl Chloride and CryoDose TA ingredients are equivalent in skin surface temperature reduction.
- CryoDose TA is non-flammable, non-HAZMAT, non-toxic, and carries no inhalation precautions for your staff or patients. It is safe to be used in confined spaces like exam rooms.
- Improved delivery system: CryoDose TA uses a modern aerosol canister. While the Ethyl Chloride brown glass bottle must be inverted to function, the CryoDose TA canister is held at any angle and has an accurate stream spray that is more intuitive to use for staff.
- FDA rating as equal in efficacy and use to Ethyl Chloride (substantially equivalent).
Over 10,000 healthcare facilities have chosen CryoDose TA over Ethyl Chloride for a variety of reasons including Ethyl Chloride is extremely flammable and recognized as a HAZMAT substance by the CDC and OSHA. According to the EPA, “Sources of possible Ethyl Chloride exposure include the inhalation of contaminated air…” A study conducted by the National Toxicology Program (NTP) cited in the same EPA paper, indicated that inhaled Ethyl Chloride is carcinogenic in female mice and may be carcinogenic in rats.
OSHA has recognized that Ethyl Chloride studies are outdated and actively refers to more up-to-date studies by The American Conference of Governmental Industrial Hygienists (ACGIH). The ACGIH has categorized Ethyl Chloride A3 – confirmed animal carcinogen with unknown relevance to humans. Ethyl Chloride’s own instructions for use include the precaution, “Use in a well-ventilated area,”* which is rarely found in the examination room of a medical practice.
*Gebauer’s Ethyl Chloride® Application Instructions
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References & Citations
Ethyl Chloride Toxicity
CDC recommends that Ethyl Chloride be treated in the workplace with caution because of its structural similarity to the four chloroethanes (ethylene dichloride; hexachloroethane; 1,1,2,2-tetrachloroethane; and 1,1,2-trichloroethane) shown to be carcinogenic in animals. Click here to learn more.
The American Conference of Governmental Industrial Hygienists (ACGIH®) carcinogenicity designation Click here to learn more.
British Journal of Anesthesia article on Ethyl Chloride as a general anesthetic. Click here to learn more.
National Toxicology Program (NTP) study indicated that inhaled Ethyl Chloride is carcinogenic in female mice and may be carcinogenic in rats. Click here to learn more.
The National Capital Poison Center (NCPC), details that in animal studies, Ethyl Chloride exposure was associated with an increase in uterine and liver tumors in female mice. Click here to learn more.
European Chemicals Agency (ECHA), the classification provided by companies to ECHA in REACH registrations identifies that Ethyl Chloride may damage fertility or the unborn child and contains gas under pressure and may explode if heated. Click here to learn more.
Ethyl Chloride Occupational Airborne Exposure Limits
OSHA The legal airborne permissible exposure limit (PEL) of Ethyl Chloride is 1,000 ppm averaged over an 8-hour work shift. Click here to learn more.
*OSHA recognizes that many of its permissible exposure limits (PELs) are outdated and inadequate for ensuring protection of worker health. OSHA recommends that employers consider using the alternative occupational exposure limits because the Agency believes that exposures above some of these alternative occupational exposure limits may be hazardous to workers, even when the exposure levels are in compliance with the relevant PELs.
ACGIH® TLV® (Threshold Limit Value) Click here to learn more.
Cal/OSHA The permissible exposure limit of Ethyl Chloride is 100ppm averaged over an 8-hour work shift. Click here to learn more.
ECHA Occupational Exposure Limits of Ethyl Chloride is 100ppm. Click here to learn more.
Ethyl Chloride Fact Sheets
EPA, Health Effects Notebook for Hazardous Air Pollutants, Ethyl Chloride Click here to learn more.
World Health Organization, INCHEM, Ethyl Chloride Click here to learn more.
Ethyl Chloride Info, State Agencies
California Office of Environmental Health Hazard Assessment (OEHHA), California Proposition 65 warning listing Ethyl Chloride as causing cancer. Click here to learn more.
New Jersey Department of Health and Senior Services, Toxic Chemical Fact Sheet, Ethyl Chloride Click here to learn more.